4-nitroquinoline n-oxide: an inhibitor of skin tumor initiation by 3,4-benzpyrene.
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منابع مشابه
4-nitroquinoline N-oxide: an Inhibitor of Benzpyrene Carcinogenesis of Mouse Skin.
The rate of appearance of papillomas on the skin of mice treated with 3,4-benzpyrene was markedly retarded by 4-nitroquinoline N-oxide, applied either in the same solution as the benzpyrene or 3 days before each benzpyrene application. Carcino genesis by 1,2,5,6-dibenzanthracene was also inhibited. No inhibition was ob served when the nitroquinoline oxide and benzpyrene were applied to separate...
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3 ,4-B e nzpy ren e , 7,1 2-dimethylbenz(a)anthracene, and 1,2-benzpyrene were topically applied to mouse skin in order to study their effects upon RNA synthesis in the latter. Both of the known carcinogenic substances [3,4-benzpyrene and 7 , 12-dimethylbenz(a)anthracene] caused a preliminary decrease in the rate of RNA synthesis, followed by an abrupt increase well above the normal rate; howev...
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ورودعنوان ژورنال:
- Cancer research
دوره 25 7 شماره
صفحات -
تاریخ انتشار 1965